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i |
Contents |
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ii |
Acknowledgement |
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iii |
Preface |
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iv |
Abbreviations |
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Abstract |
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Summary |
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Introductions |
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1.1 |
Historical Preamble |
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1.2 |
History and Geography of the Region |
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1.3 |
Demography of the Arab World and Palestine |
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1.4 |
Aims and Objectives of the Blind Schools Survey |
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Review of Literature on
Blindness |
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2.1 |
Historical Aspects and Data Collection |
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2.2 |
Blinding Conditions |
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2.3 |
Blindness Worldwide |
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2.4 |
Blindness in the
Middle East Crescent (including the Arab & Muslim World) |
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2.5 |
Childhood Blindness
Worldwide |
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2.6 |
Childhood
Blindness in the Middle East Crescent |
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2.7 |
Prevention of Blindness |
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2.8 |
Consanguinity |
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Patients and Methods |
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Results |
Of survey of childhood onset visual impairment
and blindness |
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3.1 |
Patients, Sibships and Pedigrees |
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3.2 |
Visual Acuities |
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3.3 |
Anatomical Classifications
of Causes of Visual Impairment |
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3.4 |
Aetiological Classifications
of Causes of Visual Impairment |
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3.5 |
Non-Hereditary Conditions
of Causes of Visual Impairment |
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3.6 |
Clinical Conditions in
the survey |
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3.7 |
Marriage Patterns (Consanguinty) - click for
Gaza A
pedigree chart
Jalili Syndrome |
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3.8 |
Prevalence and Family Information
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Conclusions |
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4.1 |
Discussion |
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4.2 |
Summary of Findings |
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Bibliography |
References |
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Appendices |
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ap1 |
Instruction Booklet |
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(Basic
instructions to nurses and paramedics that were used during the blind schools survey
in the West Bank
& Gaza Strip between October 1985 to 1987). |
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ap2 |
Proposed Prevention
Programme: Recommendations - (1987) |
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In conjunction
with Dr Peter Qumri, Consultant Surgeon, Friends of the Sick Society, Bethlehem |
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Colour Plates (Photographs) |
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a |
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Photographs
of St John Ophthalmic Hospital, Jerusalem |
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b |
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Photographs on the history of
Palestine |
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c |
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Photographs of the outpatient clinics |
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d |
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Photographs from Southern Sudan |
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e |
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Photographs on the Screening in the
Gaza Strip, 1985-1987 |
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f |
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Photographs of the Blind
schools and UNRWA Training Centre in Gaza 1985-1978 |
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g |
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Photographs of corneal infection from measles from an
epidemic in 1914 |
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h |
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Photographs of cases of trauma from bomb explosion
in Gaza Strip |
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i |
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Photographs of congenital corneal oedema |
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j |
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Photographs of syndromatic ectopia lentis
with hypogentalia |
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k |
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Photographs of advanced congenital glaucoma |
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l |
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Photographs of the spectrum of microphthalmia from Gaza
Strip |
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m |
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Photographs of albinism in large pedigrees. |
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n |
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Photographs of skin lesions in albinism. |
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o |
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Photographs of the evolution of macular
changes in cone-rd dystrophies |
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p |
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Photographs of the
evolution of lesions in amelogenesis imperfecta |
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q |
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Photographs of trichomegaly with congenital hypertrichosis
and congenital amaurosis of the cone-rod |
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r |
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Photographs of severe
photophobia improvement with dark tinted filter (red glasses) |
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s |
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Photographs of advanced metastasised
retinoblastoma in a Palestinian child (terminal) |
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t |
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Photographs of extra digits, leucocoria as a result of
optic nerve hypoplasia |
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u |
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Photographs shanty town in
Jabalia camp, 1985-1987 |
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v |
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Photographs of the states of roads in the Gaza Strip
1985-1987 |
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Pedigree Charts (Gaza
A: Cone Rod Dystrophy & Amelogenesis Imperfecta -Jalili Syndrome #1) |
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Publications arising from the study |
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Syndrome of cone-rod dystrophy and amelogenesis imperfecta (syndrome #1)
A progressive cone-rod dystrophy and
amelogenesis imperfecta: a new syndrome.
(OMIM 217080)
Jalili IK, Smith
NJD.
Journal of Medical Genetics,
l988;25:738-740. Pubmed
Central
With a great sadness we announce the
death of professor David Smith in March 2010
Increased band sharing in DNA fingerprints of an
inbred human population. Bellamy RJ, Inglehearn CF, Jalili IK,
Jeffreys AJ, Bhattacharya SS. Human Genetics 1991;87:341-347.
Linkage
Identification of a locus on chromosome 2q11 at which recessive amelogenesis imperfecta and cone-rod dystrophy cosegregate.
Downey LM,
Keen TJ, Jalili IK, McHale J, Aldred MJ, Robertson SP, Mighell A, Fayle S,
Wissinger B, Inglehearn CF. European
Journal of Human Genetics 2002:19,865-860.
Mutations
Mutations in CNNM4 Cause Jalili Syndrome, Consisting
of Autosomal-Recessive Cone-Rod Dystrophy and Amelogenesis Imperfecta
(PubMed Central)
Parry DA, Mighell
AJ, El-Sayed W, Shore RC,
Jalili IK, Dollfus H, Bloch-Zupan A,
Carlos R, Carr IM, Downey LM, Blain KM, Mansfield DC, Shahrabi M,
Heidari M, Aref P, Abbasi M, Michaelides M, Moore AT, Kirkham J, Inglehearn CF.
American Journal of Human Genetics; 2009:84:266–273.
(The gene was found simultaneously by Polok and
Colleagues. See American Journal of Human genetics. 2009,84:259-65).
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Cone-rod
congenital amaurosis with hypertrichosis and trichomegaly (syndrome #2)
Cone
rod congenital amaurosis associated with
congenital hypertrichosis: an
autosomal recessive condition.
Jalili
IK. Journal
of Medical Genetics, l989;26:504-5l0.
(Reprint
- OMIM
204110)
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Chrioretinal
macular dystrophy associated with high myopia (syndrome #3)
Congenital
onset central chorioretinal dystrophy associated with high myopia:
Iqbal M,
Jalili IK.
Eye
1998;12:260-265.
Reprint Request |
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